Lupron Depot

What is Lupron Depot?
Lupron Depot is a prescription medication for the management of endometriosis, given as an injection by a healthcare professional. It can help relieve the pain of endometriosis and reduce endometriotic lesions. Lupron Depot has been prescribed by doctors since 1990.

Lupron Depot offers 2 different dosing options for treatment, both of which can be combined with Add-back therapy from day 1 in appropriate patients:

  • Injected once every 3 months (11.25 mg dose)
  • Injected once each month (3.75 mg dose)

How Does Lupron Depot Work?
Lupron Depot therapy suppresses the signals from the pituitary gland in the brain to the ovaries, which stimulate estrogen production. By doing this, Lupron Depot injections also suppress the hormones that cause endometriosis to grow. Suppressing the hormones helps:

  • Provide endometriosis pain relief
  • Reduce endometriotic lesions

Things to keep in mind
Your estrogen levels will increase for 1 or 2 weeks after beginning Lupron Depot. During this time, you may notice an increase in your current symptoms. You should notify your doctor if you develop any new or worsened symptoms after beginning Lupron Depot treatment.

Lupron Depot is not a method of birth control. Even though you may not have a period, unprotected intercourse could result in pregnancy. You should use non-hormonal birth control such as condoms, a diaphragm with contraceptive jelly, or a copper IUD to prevent pregnancy. Contact your doctor immediately if you think you may be pregnant.

Source: Lupron GYN for Endometriosis

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