Hormone Pellet Therapy for Menopause

Hormone pellet therapy is a method of replacing hormones using implants under the skin that release bioidentical hormones derived from plants. This treatment helps alleviate menopause symptoms and can aid transgender individuals in managing sex characteristics.

What Are Hormone Pellets?

Hormone pellets are small implants that release bioidentical hormones similar to those naturally produced by the body. These compounded bioidentical hormone pellets are not FDA-approved due to a lack of evidence supporting their safety and effectiveness.


A healthcare professional numbs the skin, makes a small incision (usually in the hip area), and inserts the hormone pellets. The incision is closed with Steri-Strips or a stitch. The pellets provide a constant supply of hormones for about three months.


  • Relief from menopause symptoms
  • Improved sex drive, energy, and mood
  • Reduced body fat
  • Protection against heart disease and osteoporosis
  • Direct absorption into the bloodstream
  • Continuous hormone availability
  • No need for daily topical creams, gels, patches, or oral medication

Side Effects

Possible side effects include:

  • High LDL cholesterol
  • Male pattern baldness
  • Excessive hair growth
  • Acne and irritability
  • Vaginal bleeding or spotting
  • Breast tenderness or enlargement
  • Nausea, vomiting, and abdominal cramps
  • Weight changes and changes in libido


While some believe bioidentical hormone therapy to be safer, there is limited evidence to support this. The ACOG recommends FDA-approved hormone therapies over compounded hormone therapy.

For more information, visit Medical News Today.

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